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One of the secrets of the Old Empires that never faded away, the Proteus Nanovirus is everywhere. Some places have more advanced strains than others, and you probably don't want to subject yourself to a Metamorphosis Virus from an unproven source, but treatments like sterility after having one child, changing ones appearance like one changes your wardrobe, and even more advanced options like the a Neurovirus or a Methuselah Program can be found in many places throughout the Galaxy. This is a world where a couple might swap sexes after having a kid, or send a kid having trouble concentrating in school to the clinic to have his personality tweaked. In places with advanced Biotech, like Garden, you see people choosing to grow their own Solar Sails or deciding to really join with their partner via a Merging Virus. Even bringing back the dead isn't beyond the pale -- though results aren't always... perfect.
The simpler treatments are generally very casual; there's very little risk. Metamorphosis Treatments, though, can cause unintended changes or outright kill its patient. Accelerated Nanovirus is even regarded as dangerous! People who decide to turn themselves into human-plants or become Void Dancers either take the risk, or go for a Clinical Metamorphosis. While, a very long time ago when this was first introduced, "letting the doctors stop your life processes and put your body in nanostasis so the nanos can do their jobs more safely," was a scary thing, most people take it for granted these days. Of course, given how expensive this is, many poorer people with dreams of living underwater full-time just take their risks.
Even this assumes that you have a place to get the treatment. Many people won't trust their local facilities for a Nanovirus! There's usually some world not too far away, though, with a reputation for good facilities. "Nano-Junkies" tend to be frequent travelers, and often settle in these locations.
Some Other Nanovirus Notes