The very basics:
Temporary Willpower is health levels. Virtues are soak. (Highest? Most situationally appropriate?) Attack using Socialize/Presence/Linguistics/Performance + Manipulation or Charisma. Defend using Awareness/Socialize + Charisma or Appearance.
Socialize and Performance can attack reputation (ranged attacks; target need not be present) while Presence and Linguistics attack beliefs (melee attacks; target must be there).
Possibly no action splitting with free reflexive defenses; we'll see.
Initiative = Wits + Manipulation.
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